TLDR: Shallow Edgelord Garbage.
The protagonist is a generic transmigrator with minimal personality and little defined motivation. He's simply a sociopath who wants power for its own sake and has 0 bottom line. He is a violent and cruel monster with no redeeming qualities, whose crimes include torture and vivisection. The author is the sort who thinks that constitutes good writing.
There are no interesting side characters either. The author changes details without noting them. First he has 20 runes, then he has 13, then he has 20 again. The only thing I can say for this story is that the magic system is well thought out and defined. However, because it's edgelord garbage, it gets nothing from me.